Actin Filament Structuresand
Implications for Muscle Contraction
Place:
Renault Winery
$25 for members & guests
$10 for students
The Speaker: Kartik Narayan is a Stockton Chemistry alum who obtained his Ph.D. in 2002 from Princeton University studying the structural aspects of the motor proteins, actin and myosin, under the tutelage of Dr. CE Schutt. Subsequently, Dr. Narayan has undertaken post-doctoral studies in Stockholm University and the University of Pennsylvania, where he is investigating the cellular role of inositol phosphates in osmotic shock with Dr. Mark Lemmon.
The Talk: Despite a wealth of biochemical and structural information, the structure of filamentous actin (F-actin) remains to be elucidated. The tendency of monomeric actin to polymerize into filaments of random length precludes crystallization; therefore, models of the filamentous form of actin have been constructed using data obtained by electron microscopy and fiber diffraction of two-dimensional paracrystals as constraints. These models, however, have not definitively fit all the biochemical cross-linking data, and remain open to speculation. Until an atomic-resolution crystal structure of F-actin is determined, the mechanism of motile activity will not be solved.
The September meeting will be held at the Renault Winery
From Philly and West Jersey, take AC expressway to Egg Harbor Exit 17. Left onto Route 50, right onto Route 30. Look for large champagne bottle on left and turn left onto Bremen Ave. Go 2.25 mi to Renault.
From Atlantic City, take Route 30 West ca. 16 MI to Bremen Ave. Large champagne bottle marks the spot. Go 2.25 mi to Renault.
Please call the restaurant at 609-965-2111 for directions if needed. You can also check their web site at www.renaultwinery.com.
Dinner selections:
1. Stuffed Chicken Breast with fresh mozzarella and imported prosciutto with a tomato basil sauce and angel hair pasta
2. Pine nut crusted Chilean Sea Bass with Crab Risotto
3. Filet Mignon with whipped potatoes, seasonal vegetables and a Merlot Sauce
Please call or email your reservation by Friday, Sept 17. Be sure to indicate your dinner choice!
Reena Colacot, 609-919-3378 or reena.colacot@laureatepharma.com
Guenter Niessen 856-423-6300 or gniessen@emdchemicals.com