Physics & Astronomy
Ph.D. (Biochemistry & Molecular Biophysics) – University of Pennsylvania
NIH National Research Service Award Postdoctoral Fellow (Biophysics) – University of Pennsylvania
The physical characteristics of biological molecules underlie all of biological function. My research focuses on two key aspects of biomolecular physics: dynamic processes at the molecular level and the effects of nanoscale confinement on biomolecular associations and activity. These properties are investigated using a range of optical and nuclear magnetic resonance spectroscopic techniques.
1. Nucci, NV, Fuglestad B, Athanasoula EA, Wand AJ. Role of cavities and hydration in the pressure unfolding of T4 lysozyme. Proc Natl Acad Sci 2014 pii: 201410655 2. Marques BM*, Nucci NV*, Dodevski I, Wang KW, Athanasoula EA, Jorge C, Wand AJ. Measurement and control of pH in the aqueous interior of reverse micelles. J Phys Chem B 2014 118(8) 2020 - *contributed equally 3. Nucci NV, Pometun MS, Wand AJ. Mapping the hydration dynamics of ubiquitin. J Am Chem Soc 2011 133(32) 12326 4. Nucci NV, Pometun MS, Wand AJ. Site-resolved measurement of water-protein interactions by solution NMR 2011 18(2) 245