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The information on this page represents that of the South Jersey Section of the American Chemical Society and not necessarily that of Rowan University. Robert Newland, Councilor SJACS, takes full responsibility for the information presented.

The Speaker is a leading scientist in the field of separation science and has published over 100 technical papers and authored two books, one on practical HPLC and the other on preparative chromatography. Additionally, Brian is a well-know lecturer in and organizer of HPLC courses. These include courses for the Chromatography Forum of Delaware Valley (CFDV), the Center for Professional Advancement, the Chicago Chromatography Discussion Group (CCDG) and the American Chemical Society (ACS). Dr. Bidlingmeyer is a cum laude graduate of Kenyon College with Honors in Chemistry and received his Ph.D in Chemistry from Purdue University under Professor L. B. Rogers. Brian has served on numerous scientific councils, organization committees and advisory Boards, including the journals of Analytical Chemistry and Fresenius Journal of Analytical Chemistry. Brian is a founder and past chairman of the ACS subdivision of Separation and Purification, a past chair of the ASTM Committee E-19 on Chromatography, and a past president of the CFDV. He is also a past program chair of the Eastern Analytical Symposium (EAS) and presently serves on the executive committee. He also serves on the executive committees of the Separation subdivision of the ACS and of the CFDV. His current journal activities include being an Associate Editor and Contribution editor of the Journal of Chromatographic Science, writing a monthly column on HPLC troubleshooting, and being a member of the advisory Boards of LC/GC Magazine and of the Journal of Preparative Purification.

Brian has made significant contributions to the practice and understanding of modern HPLC. As a result of his pioneering work, he has received numerous awards in the separation science area including the Heinrich Emmanual Merck Prize for contributions to Analytical Chemistry, the International Ion Chromatography Award for contributions to that field and an IR 100 Award for a new method for amino acid analysis (“PicoTag” method). While employed by Millipore, he was awarded the Millipore Innovation Award given annually to an individual who has made key significant technical achievements to the company for that year.

Abstract: Reasonable retention with minimum tailing of organic amines is often difficult to achieve on a reversed-phase column. This is due primarily to the fact that two surfaces – an alkyl phase and a silanol surface -- are contributing to the interactions. This work demonstrates that surface silanols play a key role in determining retention on bonded phases probably through an electrostatic contribution, which would be expected from an ionized hydroxyl group existing, in essence, as an ion-exchange site. Additionally, this investigation demonstrates that the presence of surface silanols can be a major cause of excessive retention and tailing on a bonded-phase C18 column. However, contrary to popular belief, it appears that the retention and tailing are not due to the number of underlying silanols but their accessibility.
As a result of this study, we learned that it is possible to exploit the use of silanols to achieve separations of lipophilic amines on bare silica in the reversed-phase mode with minimum tailing. When using bare silica, the surface appears to act as a very weak hydrophobic, reversed-phase surface and enables the separations of organic amines that would be otherwise very difficult to achieve on a bonded C18 phase column. Just as on bonded C18 phases, retention may be adjusted on bare silica with the organic-aqueous portions of the mobile phase and with the concentration of inorganic salt in the mobile phase. The benefits of using bare silica as a reversed-phase column will be discussed.

The November meeting will be held at Adelphia Restaurant in Deptford.

The restaurant is located at 1750 Clements-Bridge Road, Deptford NJ 08096

From North Jersey, Philly, take I295 to exit 26, take Highway 42/Atlantic City Expressway south towards Atlantic City, and exit onto Highway 55. Take the first exit. Go left at the light and proceed to Clements-Bridge Road. Turn right. The restaurant is on the left side of the road and will require you to do a U-turn.

From Atlantic City, take the AC Express way to the Route 322 exit. Go through Rowan campus to route 55. Take Route 55 north to the Deptford Mall exit. Use directions above.

From Rowan, use Route 55 to go to the Deptford Mall, exit and then use the directions above.

Please call the restaurant at 856-845-8200 for directions if needed. You can also check their web site at www.adelphiarestaurant.com.

Dinner selections:
Baked Filet of Flounder with Crabmeat Stuffing and Lemon Butter Sauce
Filet Mignon
Vegetarian Meal

Special orders such as low-salt meals must be ordered in advance and may exceed the $20.00 price.

Please contact one of the people below by Friday, November 21.

Guenter Niessen (856) 423-6300 or gniessen@emscience.com