Molecular Biology

Faculty and Research Interests

Ping Jiang, MD

Assistant Professor
Director, ES Cell and Transgenics Laboratory
Department of Molecular Biology
856-566-7330
jiang@rowan.edu

Education

Shandong University School of Medicine, Jinan, Shandong, P. R. China: MD, 1983, Medicine

Massachusetts General Hospital and Harvard Medical School, Boston: MA Post-Doc 1997 Molecular and Developmental Biology

Research Interests

My laboratory, the ES Cell and Transgenics Laboratory at Rowan University School of Osteopathic Medicine, creates genetically modified mouse models for studies of human diseases and is open to the scientific communities in the United States as well as around the globe. Numerous transgenic, knockout and knockin mouse models were generated when I directed similar facilities at The Wistar Institute and Cold Spring Harbor Laboratory for over ten years.

Publications

  1. Shiyan Yu, Ghassan Yehia, Juanfei Wang, Ewa Stypulkowski, Ryotaro Sakamori, Ping Jiang, Berenice Hernandez-Enriquez, Tracy S. Tran, Edward M. Bonder, Wei Guo and Nan Gao. Global Ablation of the Mouse Rab11a Gene Impairs Early Embryogenesis and Matrix Metalloproteinase Secretion. J Biol Chem (2014) 289 (46):32030-43 [doi: 10.1074/jbc.M113.538223. Epub 2014 Sep 30]
  2. Haikun Wang, Jianlin Geng, Xiaomin Wen, Enguang Bi, Andrew V Kossenkov, Amaya I Wolf, Jeroen Tas, Youn Soo Choi, Hiroshi Takata, Timothy J Day, Li-Yuan Chang, Stephanie L Sprout, Emily K Becker, Jessica Willen, Lifeng Tian, Xinxin Wang, Changchun Xiao, Ping Jiang, Shane Crotty, Gabriel D Victora, Louise C Showe, Haley O Tucker, Jan Erikson & Hui Hu. The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nature Immunology (2014) 5(7):667-75 [doi: 10.1038/ni.2890. Epub 2014 May 25]
  3. Feng Li, Samsudeen Ponissery-Saidu, Karen K. Yee, Hong Wang, Meng-Ling Chen, Naoko Iguchi, Genhua Zhang, Ping Jiang, Johannes Reisert, and Liquan Huang. Heterotrimeric G protein subunit Gg13 is critical to olfaction. The Journal of Neuroscience (2013) 33(18): 7975–7984 [doi: 10.1523/JNEUROSCI.5563-12.2013]
  4. Ruisheng Song, Wei Peng, Yan Zhang, Fengxiang Lv, Hong-Kun Wu, Jiaojiao Guo, Yongxing Cao, Yanbin Pi, Xin Zhang, Li Jin, Mao Zhang, Peng Jiang, Fenghua Liu, Shaoshuai Meng, Xiuqin Zhang, Ping Jiang, Chun-Mei Cao and Rui-Ping Xiao. Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders. Nature (2013) 494, 375–379 [doi:10.1038/nature11834 Epub 2013 Jan 27]
  5. Chun Zhou, Silvia Licciulli, Jacqueline L. Avila, Miyoung Cho, Scott Troutman, Ping Jiang, Steven M. Albelda and Joseph L. Kissil. The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene (2013) 32(7): 903-9 [doi: 10.1038/onc.2012.99. Epub 2012 Mar 19]
  6. Chaomei Xiang, Valérie Baubet, Sharmistha Pal, Laura Holderbaum, Valérie Tatard, Ping Jiang, Ramana Davuluri and Nadia Dahmane. RP58/ZNF238 Directly Modulates Proneurogenic Gene Levels and Is Required for Neuronal Differentiation and Brain Expansion. Cell Death and Differentiation (2012) 19(4): 692-702 [doi: 10.1038/cdd.2011.144. Epub 2011 Nov 18]
  7. Ping Jiang, Jihwan Song, Esfir Slonimsky, En Li and Nadia Rosenthal. Targeted Deletion of the MLC1/3 Enhancer Results in Precocious muscle Gene Expression and Mesoderm Ablation. Developmental Biology 243: 281-293, 2002.
  8. Rakesh K. Jain, Nina Safabakhsh, Axel Sckell, Yi Chen, Ping Jiang, Laura Benjamin, Fan Yuan and Eli Keshet. Endothelial Cell Death, Angiogenesis and Microvascular Function after Castration in an Androgen-Dependent Tumor: Role of Vascular Endothelial Growth Factor. Proceeding of the National Academy of Sciences of USA 95(18): 10820-10825, 1998
  9. Jens Vanselow, Ed Grabczyk, Ping Jiang, Manfred Baetscher, Sally Teng and Mark C. Fishman. GAP-43 in Transgenic Mice: Dispersed Genomic Sequences Confer a GAP-43-like Expression Pattern During Development and Regeneration. The Journal of Neuroscience 14(2): 499-510, 1994
  10. Ping Jiang, Joel F. Schildbach, Shy-yu Shaw, Thomas Quertermous, Jiri Novoty, Robert Bruccoleri and Michael N. Margolies. Effect of Heavy Chain Signal Peptide Mutations and N-terminal chain length on Binding of Antidigoxin Antibodies. The Journal of Biological Chemistry 268: 23000-23007, 1993
  11. Raphael C. Lee and Ping Jiang. Calcium Antagonists Retard Extracellular Matrix Production in Connective Tissue Equivalent. Journal of Surgical Research 49: 463-466, 1990
  12. Shao Qingyu, Ping Jiang, Chen Kang, Zhou Hongjun, Li Jiangang, Yu Qianhui, Liu Yi and Shao Jianhua, Zhu Xinglei, Wang Keping, Wang Jinduo. A System for Detection and Analysis of Ventricular Late Potentials on the Body Surface. Chinese Journal of Biomedical Engineering 10(4): 215-221, 1991

 

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