Research at Rowan University Stratford

Science Building

Improving the health of individuals and communities begins with research. The academic departments at the School of Osteopathic Medicine consist of dedicated clinical and biomedical scientists with expertise in diverse disciplines.
Faculty-driven research in Stratford encompasses social, behavioral, clinical, and basic sciences and occurs at several sites on the campus. The New Jersey Institute for Successful Aging (NJISA) is a multi-disciplinary research institute devoted to improving the health of the elderly. The CARES Institute is a nationally-recognized center for the study of child abuse and prevention.

The Science Center houses over twenty independent basic science laboratories conducting research in biochemistry, cell biology, molecular biology, genetics and physiology. These research programs are sponsored by the National Institutes of Health, the National Science Foundation, the American Cancer Society and many other public and private entities. In addition, the Rowan University Graduate School of Biomedical Sciences integrates research with teaching. Collaboration among students, technicians, fellows, and faculty create a exciting environment for innovation and discovery.

 

Stratford Campus Research Day

The 18th Annual Stratford Campus Research Day will be held on Thursday, May 8, 2014 from 10:00am to 3:00pm in the Multi-Purpose Room of the Academic Center Building.  The purpose of this event, sponsored by Rowan-SOM, is to recognize the efforts of faculty, staff, and students involved in research, promote collaboration, and encourage student participation in research.

You are invited to submit poster presentations of research projects or related professional activity.  Poster submissions from all campuses at Rowan University are welcome. Poster space will be limited – please email Marion Dugan ( duganmc@rowan.edu ) by Thursday, April 24, 2014 regarding the number of poster presentations (including titles and authors) which you plan to submit.

In addition to poster presentations and a student poster competition, we will also have a Keynote Lecture by Dr. Guenther Boden, MD from 12pm to 1pm in the Academic Center Auditorium.  Dr. Boden is the Laura H. Carnell Professor of Medicine, Emeritus at Temple University and is a long time Temple Clinical Endocrinologist.  The title of his lecture is “Insulin Resistance, the Link between Obesity and Cardiovascular Disease.” Lunch will be provided after the keynote.

There will also be exhibits by scientific/laboratory equipment vendors.

 

Summer Medical Research Fellowship (SMRF) Program 2014

The 2014 application deadline has passed. Applications are currently being reviewed. 

 

Publication Highlights

  • Biswas-Fiss, EE, Affet, S., Ha, M., Biswas, S.B. Retinoid Binding Properties of Nucleotide Binding Domain 1 of the Stargardt Disease Associated ABC Transporter, ABCA4. J Biol Chem. 287, 44097-44107  PMID:23144455, 2012.
  • Cooper, K.F., Scarnati, M.S., Krasley, E., Mallory, M.J., Jin, C., Law, M.J. and Strich, R. Oxidative stress-induced nuclear to cytoplasmic relocalization is required for Not4-dependent cyclin C destruction. JCS. 125 1015-1026 PMID:22421358, 2012.
  • Fischer, J.A. and Muller-Weeks, S. Physician perceptions of the role and value of basic science knowledge in daily clinical practice. Medical Teacher. 34:744-747, 2012.
  • Guo, Y., Chen, X. and Ellis, R. E. Evolutionary Change Within a Bipotential Switch Shaped the Sperm/Oocyte Decision in Hermaphroditic Nematodes. PLoS Genet.  9: e1003850, 2013.

  • Krishnan, H., Ochoa-Alvarez, J.A., Shen, Y., Nevel, E., Lakshminarayanan, M., Williams, M.C., Ramirez, M.I., Miller, W.T., Goldberg, G.S. Serines in the Intracellular Tail of Podoplanin (PDPN) Regulate Cell Motility. Journal of Biological Chemistry, 288, 12215-1222, 2013. (published as “report” - reserved for “topics of exceptional novelty, significance and broad interest…within the top 5 percent of all articles published in the journal.”)
  • Law, M.J., Mallory MJ, Dunbrack RL Jr, Strich R.  Acetylation of the transcriptional repressor Ume6p allows efficient promoter release and timely induction of the meiotic transient transcription program in yeast. Mol Cell Biol. Feb;34(4):631-42, 2014.

  • Leone, P.A., Shera D, McPhee SWJ, Francis, J.S., Kolodny EH, Bilaniuk LT, Wang DJ, Assadi M, Goldfard O, Goldman HW, Freese A, Young D, During MJ, Samulski RJ, Janson CG.   Long-term follow-up after gene therapy for Canavan Disease.  Science Transl Med, 4(165), Dec 2012.

  • Vadla B, Kemper K, Alaimo J, Heine C, Moss, E.G. lin-28 Controls the Succession of Cell Fate Choices via Two Distinct Activities. PLoS Genet.  8(3): e1002588. doi:10.1371/journal.pgen.1002588, 2012.

  • Acharya NK, Levin EC, Clifford PM, Han M, Tourtellotte R, Chamberlain D, Pollaro M, Coretti NJ, Kosciuk MC, Nagele EP, Demarshall C, Freeman T, Shi Y, Guan C, Macphee CH, Wilensky RL, Nagele, R.G. Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib. J Alzheimers Dis, 35(1): 179-98, January 2013
  • Neary, C.L. and J.G. Pastorino. Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells. J. Cell Physiol. 228:1943-1948, 2013.
  • Pestov, D.G., Shcherbik, N. Rapid cytoplasmic turnover of yeast ribosomes in response to rapamycin inhibition of TOR. Mol Cell Biol, 32(11): 2135-44, June 2012.

  • Rodriguez AR, Spur, B.W.  Total synthesis of Resolvin D1, a potent anti-inflammatory lipid mediator.  Tetrahedron Letters, 53(51): 6990-4, December 2012.

  • Wu B, Walker JA, Temmermand D, Mian K, Spur, B.W, Rodriguez A, Stein TP, Banerjee P, Yin K. Lipoxin A(4) promotes more complete inflammation resolution in sepsis compared to stable lipoxin A(4) analog. Prostaglandins Leukot Essent Fatty Acids, 89(1): 47-53, July 2013.

  • Ringel R, Sologub M, Morozov YI, Litonin D, Cramer P, Temiakov, D. Structure of human mitochondrial RNA polymerase. Nature, 478: 269-73, October 2011.

  • Schwinghammer K, Cheung ACM, Morozov YI, Agaronyan K, Temiakov, D., Cramer P. Structure of human mitochondrial RNA polymerase elongation complex. Nat Struct Mol Biol, 20(11): 1298-303, November 2013.
  • Cares Institute
  • New Jersey Institute for Successful Aging
  • Graduate School for Biological Sciences

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